The Global Ocean Oxygen Network (GO2NE) is a IOC working group created in 2016 to help Member States address growing concerns about declining oxygen levels in the global ocean. Currently, the members of the core working group represent 21 institutions in 11 countries. In January 2018, this Network published a paper in Science that showed the amount of water in the open ocean with zero oxygen has gone up more than fourfold in the past 50 years. In coastal water bodies, including estuaries and seas, low-oxygen sites have increased more than 10-fold since 1950. Deoxygenation is worsening mainly because of increasing global temperatures (CO2-induced warming) and increasing loads of nutrients from agriculture, sewage, and industrial waste, including pollution from power generation from fossil fuels and biomass. Scientists expect oxygen to continue dropping even outside these zones as Earth warms. To halt the decline, the world needs to rein in both climate change and nutrient pollution. The Network offers scientific advice to policy makers to counter this concerning trend and to preserve marine resources in the presence of deoxygenation.